Research specialist position (role in the project: Technician)
Recruitment for the project “RNA and Cell Biology Platform for Research and Innovation in Medicine (RACE-PRIME)” (grant agreement no. FENG.02.01-IP.05-T003/23) implemented within the framework of the International Research Agendas funded by the European Funds for Smart Economy programme, for the position of Research specialist to carry out research work in the RNA area under the direction of Prof. Gracjan Michlewski, head of the RNA-Protein Interactions - Dioscuri Centre at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), in collaboration with Prof. Marcin Nowotny (Laboratory of Protein Structure).
The main objective of RACE-PRIME is to transform the IIMCB into a world-class center of excellence in RNA and cell biology. The premise of RACE-PRIME is the translational use of the results of basic research, e.g. to develop the premise of new therapies, diagnostic methods, discover new therapeutic objectives or to identify molecules with desirable properties so that they can be developed into medications.
Description of the project area: RNA-dependent RNA polymerases (RdRPs) are present in all RNA viruses and are therefore important targets for developing substances with potential antiviral activity. The goal of the project is to study RdRPs from a number of RNA viruses that are human pathogens. They will be used to study the mechanism of action of polymerases and their inhibitors. The approaches used will be structural biology (protein crystallography and cryo-EM) and biochemical methods.
Job description: Preparation of expression constructs, expression of viral proteins in bacterial
and eukaryotic systems, protein purification and characterization of protein-nucleic acid interactions, structural studies of viral proteins.
Requirements:
Selection criteria:
Candidates will be selected through an open competition, in accordance with the principles set out in the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers, which are part of the HR Excellence in Research strategy. https://shorturl.at/fjot2
We offer:
Deadline for applications is August 31st, 2024. Job starting date is October 1st, 2024 or as soon
as possible after this date.
How to apply:
The competition may be extended until a candidate meeting all requirements is found.
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