Junior research specialist (role in the project: Technician)
Recruitment for the project “RNA and Cell Biology Platform for Research and Innovation in Medicine (RACE-PRIME)” (grant agreement no. FENG.02.01-IP.05-T003/23) implemented within the framework
of the International Research Agendas funded by the European Funds for Smart Economy programme,
for the Junior research specialist to carry out research work in the RNA area under the direction of Prof. Gracjan Michlewski, head of the Laboratory of RNA-Protein Interactions - Dioscuri Centre in collaboration with Dr. Ewelina Małecka (Laboratory of Single-Molecule Biophysics) at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB).
The main objective of RACE-PRIME is to transform the IIMCB into a world-class center of excellence in RNA and cell biology. The premise of RACE-PRIME is the translational use of the results of basic research, e.g. to develop the premise of new therapies, and diagnostic methods, discover new therapeutic objectives or identify molecules with desirable properties so that they can be developed into medications.
Description of the project area: Antibiotic resistance arises as bacteria evolve in response to antibiotics, leading to increased healthcare costs, prolonged hospital stays, and higher mortality rates. Phages, as an alternative to antibiotics, carry genes that modify the host bacteria's translation processes to favor their transcripts. Given the differences between bacterial and human translation, studying how phages disrupt these mechanisms could reveal innovative therapeutic strategies that target bacteria without affecting human protein synthesis. This project seeks to identify phage proteins associated with ribosomal fractions using mass spectrometry and to investigate their impact on bacterial translation.
Job description: The junior research specialist will be responsible for working with bacteriophages, conducting bacterial infections, purifying ribosomes, performing single-molecule microscopy assays and other biochemical tests, as well as analyzing data.
Requirements:
Selection criteria:
Candidates will be selected through an open competition, in accordance with the principles set out in the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers, which are part of the HR Excellence in Research strategy. https://shorturl.at/fjot2
We offer:
Applications can be submitted until February 11th, 2025. The proposed start date of employment is March 1st, 2025.
How to apply:
The competition may be extended until a candidate meeting all requirements is found.
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