The Laboratory of Cellular Proteostasis at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw led by Dr. Lidia Wrobel is seeking a highly motivated, creative, and independent Postdoctoral Researcher to join our team.
You will join the project entitled “Subcellular localization and function of the ubiquitin-proteasome system in aging and neurodegeneration” carried out as the SONATA BIS grant no 2025/58/E/NZ3/00511 of the National Science Centre, Poland led by Dr. Lidia Wrobel.
As a Postdoctoral Researcher in our group, you will be responsible for the development and implementation of state-of-the-art human neuronal models of ageing and neurodegeneration, using induced pluripotent stem cells (iPSCs) and patient-derived fibroblasts. Your research will focus on understanding how the Ubiquitin–Proteasome System changes during neuronal ageing and in neurodegenerative diseases.
You will apply genome-wide CRISPR‑Cas9 screening approaches to identify novel regulators of proteasome activity and investigate how modulation of these factors can restore proteasome function in ageing and diseased neurons. The ultimate goal of this work is to uncover new therapeutic strategies for neurodegenerative disorders.
The position offers the opportunity to work at the interface of stem cell biology, functional genomics, and neurodegeneration research, within a multidisciplinary and collaborative research environment.
The ideal candidate should be able to pursue challenging tasks and achieve objectives and collaborate with other researchers. Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.
Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.
Deadline for applications is August 16th, 2026. Job starting date is September 1st, 2026 or later.
The competition may be extended until a suitable candidate who fulfils all requirements is found.
Źródło
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