The Nencki Institute of Experimental Biology PAS is seeking
a candidate for the position of:
Number of available positions: 1
Place of work: Laboratory of Protein Homeostasis
Researcher career profiles (R1-R4): R2
Field of science: Molecular biology, Biochemistry, Cell biology
Type of recruitment: An open competition complying with HR Excellence in Research rules
Scope of the project:
The Postdoctoral Researcher will be involved in the realization of the Sonata BIS project ‘Ubiquitin as a modulator of the mitochondrial protein import process’ founded by the National Science Center. The project focuses on quality control mechanisms in the biogenesis of the mitochondrial proteome. Most mitochondrial proteins originate from the cytosol and require active import into the organelle. Efficient regulation and quality control of the protein translocation process is vital for the maintenance of protein homeostasis (proteostasis) and cell fitness. Multiple lines of evidence indicate the role of the cytosolic ubiquitin-proteasome system in the regulation of mitochondrial precursor proteins. Our recent observation indicates that the attachment of ubiquitin can directly interfere with the import of a precursor protein. Thus, we hypothesize a new role for ubiquitination as a direct regulator of mitochondrial precursor proteins import. The main objective of the project is to uncover how precursor proteins that utilize different mitochondrial import pathways are affected by ubiquitination. We will also identify the factors that regulate this process at the molecular level, and aim to understand their role in physiology and pathology. The study will use human cell lines as a model system, supported by the experiments using yeast Saccharomyces cerevisiae.
Key responsibilities of the Postdoctoral Researcher include:
Full-time employment contract. Gross salary of up to 8 300 PLN per month.
Job starting date: October 1st, 2020
Duration of the position of up to four years.
Application procedure and deadline:
Closing date for applications: August 27th, 2020. We continuously monitor applications and may consider applications submitted after the deadline until the position is filled. We will contact the selected candidates only.
Applications should be sent to email@example.com Please, use ”Postdoc Proteostasis” as a title of your message
- Participation in an exciting research project
- Work in a young, active team in the excellent scientific environment and with good access to research infrastructure
- Participation in courses and conferences
Required documents (in English):
Substantive inquiries can be addressed directly to the project leader Dr. Piotr Brągoszewski firstname.lastname@example.org
Link to website: http://en.nencki.edu.pl/laboratory-of-protein-homeostasis
Please include the following clause in your CV:
“I give consent for my personal data included in the recruitment form to be processed by Nencki Institute of Experimental Biology PAS with its registered seat in Warsaw at Pasteur Street No. 3 (data controller) for the purposes of recruitment for First TEAM project pursuant to Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and to the free movement of such data, and repealing Directive 95/46/EC in compliance with a legal obligation to which the data controller is subject to (Art. 6 section 1 letter a) and the Act on personal data protection of 10 May 2018 (Journal of Laws of 2018, item 1000).”
The Controller of data is Nencki Institute of Experimental Biology PAS with its registered seat in Warsaw at Pasteur Street No. 3.
Contact Details of the Personal Data Protection Officer: email@example.com
Personal data in the recruitment form is collected and will be processed only for the purposes of recruitment for listed position conducted by Nencki Institute of Experimental Biology PAS.
Giving consent for the processing of your personal data is voluntary; however, it is necessary to take part in recruitment. You can withdraw your consent at any time. The withdrawal of the consent does not influence the lawfulness of any processing performed before the consent withdrawal.
Personal data collected in order to perform the recruitment process shall be processed throughout the period of time necessary for the organisation and completion of the recruitment process, as well as for considering a possible complaint; however, not longer than up to 31.01.2021.
Personal data will not be transferred to a third party.
You have the right to request the data controller for access to your personal data, to edit or limit its processing, as well as to raise an objection or transfer your data. You are also entitled to file a complaint to the supervisory body (President of the Office for Personal Data Protection).