The Nencki Institute of Experimental Biology PAS is seeking a candidate for the position of:
Number of available positions: 1
Place of work: Nencki Institute of Experimental Biology, Polish Academy of Sciences
Researcher career profiles (R1-R4): R2
Field of science: Neuroscience
Leszek Kaczmarek and Ewelina Knapska (Braincity directors)
Nencki-EMBL Center of Excellence for Neural Plasticity and Brain Disorders: BRAINCITY
Project is carried out within the MAB/IRA programme of the Foundation for Polish Science
Scope of the project:
Neuronal architecture of working memory: a combined single-neuron and network-level approach in humans.
Working memory (WM) is the capacity to manipulate information in short-term memory and use it for a goal directed behavior. WM is a key component of many cognitive processes, including inference, decision-making, mental calculations or awareness and is disrupted in many neurological and psychiatric diseases like Schizophrenia, Depression and ADHD. WM is a primary focus of research in cognitive neuroscience with more than six papers published every day. Despite this accumulation of research our knowledge about the cellular basis of WM in humans remains limited. This is because the traditional, non-invasive techniques employed in the field of cognitive neuroscience lack the resolution necessary to study this aspect of the human brain.
The main objective of the project is to provide insights into the neuronal mechanisms of WM at the single-neuron level and translate these results into network-level knowledge. Using my specialized expertise in single-neuron recording in humans I will exploit the unique opportunity to record neuronal activity in two brain structures fundamental for human WM (and those structures are also affected in Schizophrenia, Depression and ADHD): the dorsolateral prefrontal cortex (DLPFC) and dopaminergic nuclei (substantia nigra), during the surgical implantation of Deep Brain Stimulation devices in the clinic. These data, together with electrical stimulation (providing causal insight), and state of the art computational techniques will be used to create a comprehensive framework about the neuronal architecture of WM. A better understanding of the neural code of WM will aid treatments of psychiatric disorders characterized by WM deficiency.
Key responsibilities of the Postdoctoral Researcher include:
Application procedure and deadline:
Closing date for applications: May 13th, 2021.
Applications should be sent to email@example.com Please, use ”postdoc JK” as a title of your message.
Required documents (in English):
3. 2 letters of recommendation send independently to firstname.lastname@example.org
4. Copy of PhD diploma (or equivalent)
5. Contact information, including e-mail address and phone number
6. The candidates may include additional information or copies of documents/certificates in support of the application
Job starting date: May 25th, 2021
Duration of the position of up to 2,5 years.
Please include the following clause in your CV:
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